visit:
GuiProgramming - PythonInfo Wiki scroll down doon sa "GUI Design Tools and IDEs" but I prefer you should look to tkinter first, especially if you want a fast GUI development or use BOA soon. we use tkinter as our first interface because of its simplicity and cross platform. If you write a code like this:
import sys, Tkinter
Tkinter.Label(text="Welcome!").pack( )
Tkinter.Button(text="Exit", command=sys.exit).pack( )
Tkinter.mainloop( )
it will run in any platform, to simulate and test your program. I'm using now wxPython2.8 under Python2.3.3 (although there's a higher version, I have to use this because of our embedded system requirement). Wing IDE 3.0 for debugging (need license), PythonWin for quicker coding.
if you can avoid using GUI designer please do... before, I spend a month studying, testing those designers available online, still requires you to write manually... it's worth to study, may improved your skills further.